Results Of 4212 citations reviewed, 60 reports with 6404 participants were included in the meta-analysis. The secondary outcomes were opioid dose, opioid misuse, opioid craving, disability, or function. Main Outcomes and Measures The primary outcome was pain intensity. Meta-analyses were conducted using standardized mean differences in pain and opioid dose to obtain aggregate estimates of effect size with 95% CIs. Study Selection Randomized clinical trials that evaluated the use of MBTs for symptom management in adults also prescribed opioids for clinical pain.ĭata Extraction and Synthesis Independent reviewers screened citations, extracted data, and assessed risk of bias. The gray literature,, and relevant bibliographies were also searched. Search logic included (pain OR analgesia OR opioids) AND mind-body therapies. Objective To evaluate the association of MBTs with pain and opioid dose reduction in a diverse adult population with clinical pain.ĭata Sources For this systematic review and meta-analysis, the MEDLINE, Embase, Emcare, CINAHL, PsycINFO, and Cochrane Library databases were searched for English-language randomized clinical trials and systematic reviews from date of inception to March 2018. Knowing whether mind-body therapies may benefit patients treated with opioids for acute, procedural, and chronic pain conditions may be useful for prescribers, payers, policy makers, and patients. Importance Mind-body therapies (MBTs) are emerging as potential tools for addressing the opioid crisis. Shared Decision Making and Communication.Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience.Challenges in Clinical Electrocardiography.RoB for Guided Imagery StudiesĮFigure 13. Meta-analysis of Cognitive-Behavioral Therapy Studies on Pain OutcomesĮFigure 12. Meta-analysis of Suggestion Studies on Pain OutcomesĮFigure 5. Meta-analysis of Relaxation Studies on Pain OutcomesĮFigure 4. Meta-analysis of Hypnosis Studies on Pain OutcomesĮFigure 3. Meta-analysis of Meditation Studies on Pain OutcomesĮFigure 2. Findings of Therapeutic Suggestion StudiesĮFigure 1.
Characteristics of Therapeutic Suggestion StudiesĮTable 9. Findings of Guided Imagery StudiesĮTable 8. Characteristics of Guided Imagery StudiesĮTable 7. Characteristics of Relaxation StudiesĮTable 6. Characteristics of Hypnosis StudiesĮTable 5. Characteristics of Meditation StudiesĮTable 3.